Protein name:
5'-AMP-activated protein kinase subunit gamma-1 (AMPK gamma1;AMPK subunit gamma-1;AMPKg) ;
Alternative:
38 kDa subunit ;
Organism:
Pig (Sus scrofa).
General Annotation
Sub Unit:
AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1 or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic subunits (PRKAG1, PRKAG2 or PRKAG3). Interacts with FNIP1 and FNIP2.
Function:
AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.
Subcellular Location:
N/A
Protein Attributes:
50:
METVTSSDSS | SAVENEHPQD | TPESNNSVYT | SFMKSHRCYD | LIPTSSKLVV |
100:
FDTSLQVKKA | FFALVTNGVR | AAPLWDSKKQ | SFVGMLTITD | FINILHRYYK |
150:
SALVQIYELE | EHKIETWREV | YLQDSFKPLV | CISPNASLFD | AVSSLIRNKI |
200:
HRLPVIDPES | GNTLYILTHK | RILKFLKLFI | TEFPKPEFMS | KSLEELQIGT |
250:
YANIAMVRTT | TPVYVALGIF | VQHRVSALPV | VDEKGRVVDI | YSKFDVINLA |
300:
AEKTYNNLDV | SVTKALQHRS | HYFEGVLKCY | LHETLETIIN | RLVEAEVHRL |
330:
VVVDENDVVK | GIVSLSDILQ | ALVLTGGEKP |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Pig
Human
Mouse
Bovine
Rat
ELISA Kit for Pig AMPK gamma1
ELISA Kit for Pig AMPK gamma1
ELISA Kit for Pig AMPK gamma1
ELISA Kit for Pig AMPK gamma1
ELISA Kit for Pig AMPK gamma1
CLIA Kit for Pig AMPK gamma1
CLIA Kit for Pig AMPK gamma1
CLIA Kit for Pig AMPK gamma1
CLIA Kit for Pig AMPK gamma1
CLIA Kit for Pig AMPK gamma1
Polyclonal Antibody for Pig AMPK gamma1
Polyclonal Antibody for Pig AMPK gamma1
Polyclonal Antibody for Pig AMPK gamma1
Polyclonal Antibody for Pig AMPK gamma1
Polyclonal Antibody for Pig AMPK gamma1
Monoclonal Antibody for Pig AMPK gamma1
Monoclonal Antibody for Pig AMPK gamma1
Monoclonal Antibody for Pig AMPK gamma1
Monoclonal Antibody for Pig AMPK gamma1
Monoclonal Antibody for Pig AMPK gamma1
Protein for Pig AMPK gamma1
Protein for Pig AMPK gamma1
Protein for Pig AMPK gamma1
Protein for Pig AMPK gamma1
Protein for Pig AMPK gamma1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 48-58; 101-113; 153-169; 177-208; 225-231; 240-253 AND 300-329
tissue :
Liver .